GRAFT VERSUS HOST DISEASE- ORAL PRESENTATION

Oral features of graft-versus-host disease*

Chronic graft-versus-host disease (cGVHD) is a late complication of allogeneic hematopoietic stem cell transplant (HSCT), occurring in 18% to 70% of recipients.1-3 The oral tissues may be involved in up to 90% of the patients that present cGVHD in other organs.4-10 Oral mucosa lesions and salivary gland dysfunction are the main manifestations of oral cGVHD, but a reduction of the mouth opening ...

Graft Versus Host Disease

Commonly referred to as GVHD, graft-versus-host disease is a man-made condition that arises when patients are transplanted with donor tissue that is not identical to their own. Transplants from other individuals are called allogeneic (‘allo’ meaning ‘other’ and ‘geneic’ referring to ‘genes’). GVHD occurs after hematopoietic stem cell or bone marrow transplantation but is most commonly experienc...

Graft versus Host Disease

Definition Graft-versus-host disease (GVHD) is the most common complication of allogeneic hematopoietic stem cell transplantation (HSCT). In HSCT, the patient’s bone marrow is destroyed with chemotherapy and/or radiation and replaced by donor hematopoietic stem cells. In allogeneic HSCT the donor is usually a close family member or occasionally someone outside the family who has been found to b...

Graft-versus-host disease or graft-versus-host-like syndrome.

How we treat oral chronic graft-versus-host disease.

Chronic graft-versus-host disease (cGVHD) is a major complication of allogeneic hematopoietic cell transplantation that is associated with a diminished quality of life. The oral cavity is frequently affected, with a wide variety of signs and symptoms that can result in significant short- and long-term complications ranging from mucosal sensitivity and limited oral intake to secondary malignancy...